【摘要】 采用八通道微量热法探讨槲皮素镧配合物对粟酒裂殖酵母细胞生长代谢热动力学的影响。测定在槲皮素镧配合物作用下S.Pombe细胞的生长代谢产热曲线,并研究其生长速率常数(k)、最大发热功率(pmax)、达最大发热功率时间(tmax)和抑制率(I)等热动力学参数。微量热结果表明:随着槲皮素镧配合物浓度c的增大,最大发热功率pmax和速率常数k减小;达最大发热功率时间tmax和抑制率I增大。研究表明槲皮素镧配合物对粟酒裂殖酵母细胞生长代谢产生了抑制作用。更多还原

【Abstract】 To study the thermodynamic effect of the quercetin lanthanum complexes on proliferation of Schizosaccharomyces pombe cells, eight channels microcalorimetry was performed to determine the heat production curve of cell proliferation and metabolism after the quercetin lanthanum complexes was added, and thermodynamic parameters such as growth and metabolism rate constant(k), the maximum heating power(pmax), the max heating power time(tmax) and inhibition rate(I) were also investigated. The microcalorimetric results showed that the maximum heating power pmax and rate constant k decreased but the max heating power time tmax and inhibition rate I enlarged with the increasement of concentration c of quercetin lanthanum complexes. It could be concluded that quercetin lanthanum complexes inhibited the cell growth and metabolism of S. pombe.更多还原