【摘要】 目的探讨简易精神状态检查量表(MMSE)、蒙特列尔认知评估量表(Mo CA)评估阻塞性睡眠呼吸暂停综合征(OSAS)患者轻度认知功能障碍(MCI)的可行性。方法用便携式多导睡眠仪、MMSE及Mo CA对51名OSAS患者和35名单纯鼾症者进行睡眠监测和认知功能的评价。结果 OSAS组Mo CA评分结果为21.1±3.0,显著低于对照组的25.0±2.6(P<0.01);MMSE评分结果在OSAS组与对照组中分别为27.8±1.8及28.1±1.7,无统计学意义。结论 Mo CA对于OSAS患者MCI的早期诊断敏感性优于MMSE,对于MMSE测试结果正常但高度怀疑存在MCI者,Mo CA是一种简便可行的筛查工具。更多还原

【Abstract】 Objective Obstructive sleep apnea syndrome( OSAS) is known to be associated with impairment in cognitive function. The aim of this study is to develop a sensitive screening tool to detect mild cognitive impairment( MCI) among Chinese patients with OSAS. Methods There were totally 51 OSAS patients( OSAS group) and 35 primary snoring peoples( control group) included in the study. All of them were monitored by polysomnography( PSG),administered by the mini-mental state examination( MMSE) and the Montreal cognitive assessment( MoCA) questionnaires was applied to assess their sleep condition and cognitive function. Results Compared with control group,the score of Mo CA in OSAS group was 21. 1 ± 3. 0,strikingly lower than that of the control group25. 0 ± 2. 0( P < 0. 01),the scores of MMSE in OSAS group and control group were 27. 8 ± 1. 8 and 28. 1 ± 1. 7,the difference was of no significance. Conclusions The Mo CA is a simple and sensitive tool for the assessment of MCI in OSAS patients,whose performance on the MMSE is in the normal range.更多还原