Objective To investigate the effect of sperm DNA fragmentation index on treatment outcomes of in vitro fertilization( IVF) and intracytoplasmic sperm injection( ICSI),and to provide a reference for improving the clinical success of assisted reproduction. Methods Database in both English and Chinese,Such as Pub Med,CNKI,etc were retrieved. The literatures about the sperm DNA fragmentation index( DFI) affecting IVF and ICSI clinical outcomes were screened. Stata12. 0 software was used to analyze the extracted...
【更新日期】
2015-04-08
【分类号】
R714.8
【正文快照】
(Chin J Dis Control Prev 2015,19(3):299-303)精子DNA作为遗传物质的载体,在人类的繁衍生存中起着至关重要的作用,其完整性对精子的受精能力有一定的影响,当精子进入卵细胞后,DNA受损的精子还会影响到胚胎的发育能力,国内外都有研究表明,精子DNA的完整性与女性自然受孕率下降