Effects of Parecoxib Sodium Preemptive Analgesia on Postoperative Inflammatory Cytokines and Stress Responses in Elderly Patients Undergoing Total Hip Replacement
Objective To investigate whether parecoxib sodium preemptive analgesia reduces inflammatory cytokines and stress hormones production in elderly patients after total hip replacement. Methods Sixty patients with American Society of Anesthesiologists Classification Ⅰ- Ⅱ undergoing total hip replacement for femoral neck fracture or aseptic necrosis of the femoral head, aged between 60 and 90 years with a body weight more than 50 kg, were randomly divided into preemptive analgesia group(group P, n=30) and contro...