【摘要】 目的研究N-甲基色胺(MT)的制备工艺及其热稳定性。方法以色胺为原料,经酰化、还原得MT,用差示扫描量热法和热重分析研究MT的热稳定性和热分解过程。结果两步工艺的总收率为72.7%,在氮气氛(氮气流量为30 m L·min-1)、10 K·min-1的升温条件下,MT在218℃时发生剧烈分解,至313℃分解完全。结论所用制备方法简单、产率良好,适合大量制备,且热稳定性良好。更多还原

【Abstract】 OBJECTIVE To study the preparation and thermostability of N- methyltryptaine( MT). METHODS MT was prepared from tryptamine followed by successive acylation,reduction reaction. Its thermostability was investigated by differential scanning calorimetry and thermogravimetry. RESULTS The overall yield of the two- step process of MT was 72. 7%. The experiments showed that the solid of MT could produce an intense thermolysis at up to 218 ℃ in nitrogen 30 m L·min- 1with a heating rate of 10 K·min- 1. 99. 9%of MT was decomposed when the temperature rose to 316 ℃. CONCLUSION MT has a good thermostability and can be obtained by tryptamine in a good yield. Hence,this preparation of MT is simple and suitable for massive industrial production.更多还原