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盐酸曲美他嗪联合美托洛尔对心梗后心衰的干预作用研究
Hydrochloride Trimetazidine Joint Metoprolol Intervention on Patients with Heart Failure After Myocardial Infarction
【摘要】 目的探讨盐酸曲美他嗪联合美托洛尔对心梗后患者心衰的干预作用。方法将我院心血管科收治的心梗后心衰患者106例按Doll’s随机数字表法分为对照组和治疗组,对照组给予基础治疗,治疗组在对照组药物的基础上加用盐酸曲美他嗪和美托洛尔。测定治疗前后患者的LVEDD、LVESD、LVEF和NYHA心功能分级,并对比分析两组疗效差异。结果对照组显效33例,有效7例,无效13例,总有效率75.47%;治疗组显效45例,有效4例,无效4例,总有效率92.45%。治疗组总有效率高于对照组,两组治疗前后差异有统计学意义(P<0.05)。结论盐酸曲美他嗪联合美托洛尔能改善心梗后心衰患者的心脏射血和心血管功能,对心梗后患者心衰有显著疗效。
【Abstract】 Objective To explore the hydrochloride trimetazidine joint metoprolol intervention for patients with heart failure after myocardial infarction. Methods Selecting 106 cases with heart failure after myocardial infarction by Doll’s random number table method in the hospital and dividing them into two groups. Control group were given basic treatment,and treatment group were combined with trimetazidine hydrochloride and metoprolol. Measuring the level of function classification with LVEDD,LVESD,LVEF and NYHA,and comparing curative effects of two groups. Results In the control group,there were 33 markedly effective cases,7 effective cases,and 13 ineffective cases.The total effective rate was 75. 47%. 45 cases in the treatment group were markedly effective,4 cases were effective,and 4 cases were ineffective. The total effective rate was 92. 45%. Treatment group total effective rate was higher than the control group. Difference of two groups before and after treatment was statistically significant( P < 0. 05). Conclusion Hydrochloride trimetazidine joint metoprolol can improve heart failure after myocardial infarction in patients with cardiac ejection and cardiovascular function,has significant curative effect for patients with heart failure after myocardial infarction.
【Key words】 Trimetazidine; Metoprolol; Myocardial infarction; Heart failure;
- 【文献出处】 黑龙江医学 ,Heilongjiang Medical Journal , 编辑部邮箱 ,2015年02期
- 【分类号】R541.6;R541.4
- 【被引频次】6
- 【下载频次】68