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醋酸奥曲肽联合硝酸甘油治疗肝硬化继发上消化道出血的临床疗效观察

Clinical Efficacy of Octreotide Acetate Combined Nitroglycerin Treatment of Cirrhosis Secondary to Gastrointestinal Bleeding

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【作者】 韩金利才洪良刘宇红蒋晶超孙雪丹

【Author】 HAN Jinli;CAI Hongliang;LIU Yuhong;The Harbin 242 Hospital of AVIC;

【机构】 中航工业哈尔滨二四二医院

【摘要】 目的探讨醋酸奥曲肽联合硝酸甘油治疗肝硬化继发上消化道出血的临床疗效。方法选择收治的肝硬化继发上消化道出血患者84例,将其平均分为研究组与对照组。两组患者均采取积极的综合治疗,在此基础上,对照组应用醋酸奥曲肽治疗,研究组在对照组的基础上给予硝酸甘油治疗。结果研究组治疗的总有效率为95.24%,显著高于对照组的80.95%(P<0.05);研究组平均止血时间为(10.2±2.5)h,低于对照组为(15.5±2.6)h(P<0.05);两组药物不良反应对比差异无统计学意义(P>0.05)。结论醋酸奥曲肽联合硝酸甘油治疗肝硬化继发上消化道出血疗效确切,安全可靠,适于临床应用。

【Abstract】 Objective To discuss the Clinical efficacy of Octreotide acetate combined Nitroglycerin treatment of Cirrhosis secondary to gastrointestinal bleeding. Methods 84 patients of Cirrhosis secondary to gastrointestinal bleeding in our hospital,which were randomly divided into study group and control group. Both groups were proactive comprehensive treatment. Based on this,control group was given Octreotide acetate treatment,study group was given nitroglycerin treatment on the basis of the control group. Results The total effective rate was 95. 24 percent in study group,significantly higher than the effective rate of 80. 95%( P < 0. 05) in the control group; The average bleeding time of the study group is( 10. 2 ± 2. 5) h,Lower than the average bleeding time in control group( 15. 5 ± 2. 6) h( P < 0. 05); Comparison of adverse drug reactions in two groups showed no significant difference( P > 0. 05). Conclusions Octreotide acetate combined Nitroglycerin treatment of Cirrhosis secondary to gastrointestinal bleeding is effective,safe and reliable,suitable for clinical application.

  • 【文献出处】 航空航天医学杂志 ,Journal of Aerospace Medicine , 编辑部邮箱 ,2015年12期
  • 【分类号】R573.2;R575.2
  • 【被引频次】8
  • 【下载频次】31
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