【摘要】 目的评价脑脊液改良抗酸染色法与实时荧光定量聚合酶链反应(fluorescence quantitative polymerase chain reaction,FQ-PCR)法诊断结核性脑膜炎(tuberculous meningitis,TBM)的意义。方法 TBM患者81例,采集脑脊液检测标本,分别采用离心甩片改良抗酸染色法、实时FQ-PCR法检测抗酸杆菌。结果 81例改良抗酸染色法阳性率66.7%(54/81)高于FQ-PCR方法阳性率50.6%(41/81),差异有统计学意义(P<0.05)。结论在诊断TBM方面,改良抗酸染色方法显著优于FQ-PCR方法。更多还原

【Abstract】 Objective To evaluate united test significance in the diagnosis of tuberculous meningitis(TBM) with modified acid-fast staining method of cerebrospinal fluid and real-time fluorescence quantitative polymerase chain reaction(FQ-PCR).Methods Cerebrospinal fluid samples from 81 patients with TBM were detected for Mycobacterium tuberculosis respectively with centrifugal modified acid-fast staining method and real-time FQ-PCR.Results The positive rate of modified acid-fast staining 66.7%(54/81) was significantly higher than that of FQ-PCR50.6%(41/81),there was significant difference between the two methods(P<0.05).Conclusion Modified acid-fast staining method is significantly better than FQ-PCR in the diagnosis of TBM.更多还原