【摘要】 目的:探讨湖北地区13例眼眶转移癌的原发部位、影像学表现、治疗转归等临床特征。方法:回顾性分析武汉大学人民医院眼科中心2000年12月至2014年12月期间经过手术后病理明确诊断的13例眼眶转移癌的临床表现、原发部位和影像学表现等。结果:这项研究包括8名男性和5名女性,年龄范围36-72岁(平均50.4岁)。所有的患者来自湖北地区。其中原发肿瘤最常见的是肺癌5例(38.5%),其次是乳腺癌2例(15.4%),肝癌2例(15.4%),胃癌、结肠癌、甲状腺癌、子宫恶性平滑肌肉瘤各1例(7.7%)。最常见的临床表现是眼球突出(84.6%)、眼球运动受限(69.2%)、复视(61.5%)、眼睑肿胀(38.5%)、视力下降(38.5%)和结膜充血(23.1%)。主要治疗包括手术切除、放疗、全身化疗和观察。有随访资料的10例(76.9%)患者(平均随访时间23.5个月)。结论:在湖北地区眼眶转移癌最常见的原发性癌症为肺癌,其次是乳腺癌和肝癌。眼眶转移癌可有多种临床表现,全身性肿瘤患者出现上述临床表现时需考虑此病。该病的预后普遍较差,手术可以改善其生存质量。更多还原

【Abstract】 Objective:To study the primary location,clinical characteristics,imaging findings of orbital metastatic tumors in Hubei province of China.Methods:The clinical features,the primary location and outcomes of 13 cases of metastatic orbital tumors admitted to our department from January 2000 to January 2014 were reviewed retrospectively.Results:The study included 8men and 5women.All patients were from Hubei Province.All the patients were performed the surgery.There were 5cases(38.5%)derived from lungs cancer,2cases(15.4%)from breast cancer,2cases(15.4%)from liver cancer and 1case(7.7%)from stomach cancer,colon cancer,malignant uterine leiomyosarcoma and thyroid cancer each.The most frequent ocular signs were proptosis(84.6%),limited ocular movement(69.2%),diplopia(61.5%),eyelid swelling(38.5%),decreased visual acuity(38.5%)and conjunctival hyperemia(23.1%).The main treatment included surgical excision,radiotherapy,chemotherapy and observation.Conclusion:The most common primary cancer that metastases to the ortibal is lung cancer followed by breast cancer and liver cancer in Hubei Province.Orbital metastasis can display a variety of clinical features and should be considered in patients with known systemic cancer.The systemic prognosis is generally poor and surgery can improve their quality of life.更多还原