【摘要】 目的分析乳腺实性肿物患者的性激素水平及人格分型,并探讨二者之间的关系。方法以2010年1月至2014年4月福田区乳腺实性肿物患者200例为观察组,同时抽取同期行健康体检者200例为对照组。比较两组受试者的雌二醇(E2)、睾丸酮(T)、催乳素(PRL)水平及人格分型。同时分析比较不同人格分型患者的性激素水平。结果 (1)观察组患者中人格不稳定型占59.0%,明显高于对照组的45.5%,两组比较差异有统计学意义(P<0.05);(2)观察组患者的E2、PRL分别为(67.46±22.65)pg/ml、(14.30±7.07)ng/ml,对照组分别为(66.38±22.76)pg/ml、(13.95±3.20)ng/ml,两组比较差异均无统计学意义(P>0.05),而观察组患者的T水平为(0.28±0.11)ng/ml,明显高于对照组的(0.25±0.09)ng/ml,差异有统计学意义(P<0.05);(3)不稳定型患者的E2、T和PRL分别为(67.34±22.81)pg/ml、(14.22±6.73)ng/ml和(0.27±0.10)ng/ml,与稳定型患者的(66.46±22.59)pg/ml、(14.03±3.66)ng/ml及(0.26±0.10)ng/ml比较,差异均无统计学意义(P>0.05)。结论激素T水平升高及人格为不稳定型均可以作为早期乳腺疾病筛查的指标。更多还原

【Abstract】 Objective To investigate the relationship between sex hormone levels and personality in patients with breast neoplasm. Methods Two hundred patients with breast neoplasm in out hospital from January 2010 to April 2014 were enrolled as the observation group, and 200 healthy individuals during the same period were considered as the control group. The levels of estradiol(E2), testosterone(T), prolactin(PRL) and personality in two groups were compared. Sex hormone levels of different personality types were analyzed and compared. Results(1) The patients of unstable personality type accounted for 59.0%(118/200) in the observation group and 45.5% in the control group,with statistically significant significance between the two groups(P<0.05).(2) The E2, PRL was(67.46±22.65) pg/ml,(14.30 ± 7.07) ng/ml in the observation group and(66.38 ± 22.76) pg/ml,(13.95 ± 3.20) ng/ml in the control group,with no statistically significant difference between the two groups(P>0.05). T horizontal in observation group was(0.28±0.11) ng/ml, significantly higher than(0.25±0.09) ng/ml in the control group(P<0.05).(3) The E2, T, PRL levels were(67.34±22.81) pg/ml,(14.22±6.73) ng/ml and(0.27±0.10) ng/ml for patients of unstable personality type, and(66.46±22.59) pg/ml,(14.03±3.66) ng/ml and(0.26±0.10) ng/ml for patients of stable personality type, showing no statistically significant difference(P>0.05). Conclusion Elevated T hormone levels and personality unstable type can be used as indicators for the screening of early mammary gland diseases.更多还原