节点文献

血府逐瘀汤联合硝苯地平治疗高血压脑出血非手术患者的前瞻性随机对照研究

Xuefuzhuyu Decoction combined with Nifedipine for treatment of hypertensive intracerebral hemorrhage in non-surgical patients: a prospective randomized controlled study

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 黄穗翔叶劲超陈伟新赖志强

【Author】 Huang Suixiang;Ye Jinchao;Chen Weixin;Lai Zhiqiang;Department of Surgery,Guangzhou Red Cross Hospital Affiliated to Jinan University;Department of Medicine Wenquan County Health Center of Conghua District;

【机构】 暨南大学医学院附属广州市红十字会医院外科从化区温泉镇卫生院内科

【摘要】 目的:评价血府逐瘀汤联合硝苯地平治疗高血压脑出血非手术患者的疗效。方法:将本院2013年9月-2014年10月收治的98例高血压脑出血非手术患者随机分为两组,西医组仅给予常规西医治疗,中西医组在西医治疗基础上,增加血府逐瘀汤。6月后评估两组治疗效果。结果:治疗后,中西医组收缩压(139.3±9.5 vs 161.7±11.4)mm Hg显著低于西医组,其他指标舒张压、K+(mmol/L)、Na+(mmol/L)、Cl-(mmol/L)、BUN(mmol/L)、Cr(μmol/L)两组间差异无统计学意义(P>0.05)。治疗后,中西医组痊愈20例,显效18例,有效10例,总有效率98%。西医组痊愈9例,显效12例,有效20例,总有效率84%,中西医组总有效率高于西医组,差异有统计学意义(χ2=48,P<0.05)。结论:血府逐瘀汤联合硝苯地平能有效改善高血压脑出血非手术患者的临床疗效。

【Abstract】 Objective: To evaluate the effects of Xuefuzhuyu Decoction combined with Nifedipine for treatment of hypertensive intracerebral hemorrhage( HICH) in non-surgical patients. Methods: Nighty-eight HICH patients During September 2013 to October 2014 in our hospital who did not received surgical treatment were randomly divided into two groups. The Western medicine group received conventional western medicine alone. The Chinese and Western medicine group received Xuefuzhuyu Decoction based on the treatment of western medicine. The efficacy in the two groups was assessed at 6 months after the treatment. Results: After treatment,the systolic blood pressure( SBP) in the Chinese and Western medicine group was significantly lower than that in the Western medicine group( 139. 3 ± 9. 5 vs 161. 7 ± 11. 4) mm Hg. There were no statistically significant differences in the diastolic blood pressure( DBP),K+( mmol / L),Na+( mmol/L),Cl-( mmol/L),BUN( mmol / L) and Cr( μmol / L) between the two groups( P > 0. 05). After the treatment,20 recovered,18 markedly effective and 10 effective cases were found in the Chinese and Western medicine group,with the total efficiency of 98%; 9 recovered,12 markedly effective and 20 effective cases were found in the Western medicine group,with the total efficiency of 84%. The total efficiency in the Chinese and Western medicine group was higher than that in the Western medicine group,and the difference was statistically significant( χ2= 48,P <0. 05). Conclusion: Xuefuzhuyu Decoction combined with Nifedipine can effectively improve the clinical efficacy in non-surgical HICH patients.

【基金】 广东省中医药局建设中医药强省科研课题(编号:20131157)
  • 【文献出处】 广州医科大学学报 ,Academic Journal of Guangzhou Medical University , 编辑部邮箱 ,2015年05期
  • 【分类号】R277.7
  • 【被引频次】4
  • 【下载频次】92
节点文献中: 

本文链接的文献网络图示:

本文的引文网络