【摘要】 目的探讨阿奇霉素序贯疗法治疗小儿支原体肺炎的临床效果。方法选取2012年11月~2014年11月本院诊治的支原体肺炎患儿162例,采用随机数字表法分为两组,81例患儿采用红霉素序贯疗法治疗为对照组,81例患儿采用阿奇霉素序贯疗法治疗为观察组,比较两组患儿的治疗效果。结果观察组患儿退热时间、咳嗽消失时间、肺部湿啰音消失时间、住院时间均明显少于对照组,观察组患儿治疗总有效率明显高于对照组,观察组患儿不良反应(皮疹、胃肠道反应、局部疼痛、肝功能异常)发生率均明显低于对照组,差异均有统计学意义(P<0.05)。结论阿奇霉素序贯疗法是治疗小儿支原体肺炎的有效方法,可明显改善患儿的临床病症,临床疗效显著且安全性高,值得临床推广使用。更多还原

【Abstract】 Objective To investigate clinical effect of azithromycin sequential therapy in treatment of children with mycoplasma pneumonia. Methods 162 children with mycoplasma pneumonia were selected in hospital from November 2012 to November 2014, who were randomly divided into two groups.81 patients treated erythromycin sequential therapy as control group. 81 patients treated azithromycin sequential therapy as observation group. Treatment effect was compared between two groups. Results Cooling time, cough disappearance time, lung wet rales disappearance time, hospitalization time in observation group were significantly less than control group. Total efficiency in observation group was significantly higher than control group. Incidences of adverse reactions(rashes, gastrointestinal reaction, local pain, abnormal liver function) in observation group were significantly lower than control group. Differences were statistically significant(P < 0.05). Conclusion Azithromycin sequential therapy is an effective method in treatment of children with mycoplasma pneumonia, which can significantly improve clinical symptoms. That has significant clinical effect and high security, which is worthy of clinical use.更多还原