Leptin receptor is a transmembrane receptor belonging to the class I cytokine-receptor family, which is nearly ubiquitous in central and peripheral tissues of animal, and play the decisive role in regulating physiological action.The present study was conducted to summarize recent progresses of fish's leptin receptor, including subtype classification,structural characteristic, signaling pathway, tissue distribution and regulation of gene expression. Until now, in some ways, there was still no systematic rese...
【基金】
浙江省自然科学基金项目(Y12C190001)
【更新日期】
2015-12-18
【分类号】
S917.4
【正文快照】
0引言瘦素(Leptin)是一个16 k D的蛋白激素,在哺乳动物中主要由脂肪组织产生,但鱼类瘦素m RNA在脂肪组织中缺乏表达,主要在肝脏中表达(Kurokawa etal.,2005;Gorissen et al.,2009;Li et al.,2010;Tromb-ley et al.,2012;Zhang et al.,2013)。瘦素在摄食与代谢(Ahima et al.,200
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