【摘要】 目的探讨血栓弹力图(TEG)在口服抗凝药物的良性前列腺增生(BPH)患者围手术期凝血功能状态评估中的应用价值。方法回顾性分析120例口服抗凝药物的BPH患者术中、术后出血及输血治疗情况,比较患者术后的TEG和常规凝血功能检测结果。结果术中无明显出血者,术后有明显活动性出血患者40例,无明显活动性出血患者80例;术后有明显活动性出血患者,经TEG检测发现32例(80.00%)低凝状态者,经常规凝血功能检测发现18例(45.00%)低凝状态者,2种方法检出率差异有统计学意义(χ2=12.709,P=0.002);术后无明显活动性出血患者,经TEG检测发现76例(95.00%)非低凝状态者,经常规凝血功能检测发现67例(83.75%)非低凝状态者,2种方法检出率差异有统计学意义(χ2=6.679,P=0.022)。结论 TEG检测指标能够更全面、准确地评估口服抗凝药物的BPH患者术后出血情况,指导术后输血治疗,优于常规凝血功能指标。更多还原

【Abstract】 Objective To explore the application value of thromboelastography(TEG)in perioperative evaluation of benign prostatic hyperplasia(BPH)patients treated with anticoagulants.Methods To retrospective analyze the intraoperative bleeding,postoperative bleeding and transfusion treatment of 120 patients with BPH surgery,who were treated with anticoagulants.The results of TEG detection and coagulation function test were compared.Results There was no patients with significant intraoperative bleeding,including 40 cases of bleeding after surgery,80 cases of patients with no bleeding.In patients of bleeding,there were 32 benign prostatic hyperplasia patients(80.00%)with low coagulation function detected by TEG detection,and 18(45.00%)with low coagulation function detected by routine coagulation function test.The difference of detection rates was statistical significant between the two methods(χ2=12.709,P=0.002).In patients of non-bleeding,there were 76 benign prostatic hyperplasia patients(95.00%)with non-low coagulation function detected by TEG detection,and 67(83.75%)with non-low coagulation function detected by routine coagulation function test.The difference in detection rate was significant between the two methods(χ2=6.679,P=0.022).Conclusion TEG could effectively evaluated postoperative bleeding in BPH patients,guide postoperative transfusion therapy,which is better than routine coagulation function test.更多还原