【摘要】 目的:对绝经后阴道流血(PMB)并发子宫内膜癌进行病理学研究,探讨其临床特征。方法:回顾性分析我站和靖煤集团总院2012年5月~2014年6月317例PMB患者的临床资料,根据刮宫及(或)术后病理检查结果,将PMB患者按病理学类型分为子宫内膜癌、良性病变及非器质性病变。对比子宫内膜癌与其他两类病变的临床指标,分析子宫内膜癌PMB的相关因素。结果:PMB患者中,病理学诊断为子宫内膜癌者占10.4%(33/317);子宫内膜癌PMB患者的绝经年龄、绝经年限、出血持续时间、肥胖、高血压、糖尿病比例及子宫内膜厚度与宫腔深度均高于其他病变的PMB患者,差异均有统计学意义(P<0.05)。多因素回归分析表明,子宫内膜厚度是子宫内膜癌PMB的独立相关因素(OR=3.07,95%CI=12.4~17.9,P=0.008)。结论:应纠正以往将PMB与子宫内膜癌等同的错误观点,PMB者应及早诊断,明确病因,可先行B超测量子宫内膜厚度,初步筛查子宫内膜癌后再以刮宫或术后病理诊断确诊。更多还原

【Abstract】 OBJECTIVE:To study the pathology of PMB caused by endometrial cancer and to investigate its clinical characteristics.METHODS;317 patients of PMB during May 2012-June 2014 were retrospectively analyzed.Curettage and(or) postoperative pathological diagnosis were used to determine pathology:endometrial cancer,benign or non- organic disease.A contrast of clinical indicators between endometrial cancer and the other two was carried on.RESULTS:PMB patients caused by endometrial cancer were10.4%(33/317).And their age at menopause,menopause period,bleeding duration,obesity/hypertension and diabetes rate,endometrial thickness and uterine cavity depth were all higher than those caused by benign or non- organic disease.Further studies showed that endometrial thickness was the only independent related factor of PMB caused by endometrial cancer.CONCLUSION:The view that equals PMB and endometrial cancer should be corrected and PMB should be early diagnosd to figure out its cause.更多还原