【摘要】 目的了解患者微创经皮肾镜取石术(mPCNL)术后发生尿源性脓毒血症的相关危险因素。方法收集某院1 022例患者mPCNL围手术期的临床资料,对患者mPCNL术后发生尿源性脓毒血症的危险因素进行分析。结果 1 022例患者,发生尿源性脓毒血症62例,发生率为6.07%。患者经早期发现、积极治疗后均痊愈出院。logistic逐步回归分析,结果显示,年龄(OR95%CI:1.25~3.92)、血常规(OR95%CI:1.25~14.00)、尿常规(OR95%CI:2.67~10.02)及术中灌注液体量(OR95%CI:1.37~4.18)与尿源性脓毒血症的发生密切相关。结论年龄(≥60岁)和术中灌注液体量(≥30 L)是患者mPCNL术后发生尿源性脓毒血症的危险因素;了解相关危险因素,有助于预防和及时治疗患者mPCNL术后尿源性脓毒血症。更多还原

【Abstract】 Objective To explore the risk factors for urosepsis after minimally invasive percutaneous nephrolithotomy(mPCNL).Methods Clinical data of 1 022 patients undergoing mPCNL were collected,risk factors for urosepsis after mPCNL were analyzed.Results Of 1 022 patients,62(6.07%)developed urosepsis.All patients recovered and discharged after early diagnosis and active treatment.Logistic regression analysis showed that age(OR95%CI:1.25-3.92),blood routine examination(OR95%CI:1.25-14.00),urine routine examination(OR95%CI:2.67-10.02)and volume of intraoperative fluid perfusion(OR95%CI:1.37-4.18)were closely related to urosepsis following mPCNL.Conclusion Age(≥60 years)and intraoperative perfusion fluid volume(≥30L)during operation are the risk factors for urosepsis following mPCNL,The recognition of the related risk factors is helpful for the prevention and timely treatment of urosepsis following mPCNL.更多还原