研究了Ti、Ti6Al4V和Ti6Al7Nb 3种钛基材料在喷砂酸蚀处理后成骨细胞在其表面生长的生物活性。通过Al2O3喷砂和盐酸、硫酸混合物酸蚀的表面改性方法,在Ti、Ti6Al4V和Ti6Al7Nb3种钛基材料表面进行喷砂酸蚀处理,通过SEM观察样品的表面形貌,样品的表面呈现出微米级多孔形貌;将样品浸入模拟体液(simulated body fluid,SBF)中浸泡7,14和21 d后通过SEM、X射线衍射仪(XRD)分析样品表面沉积物的形貌、物相,样品浸入SBF 14 d后,Ti6Al7Nb表面最先观察到表面覆盖的羟基磷灰石涂层;样品浸入SBF 21 d后,Ti、Ti6Al4V和Ti6Al7Nb表面都观察到羟基磷灰石涂层。羟基磷灰石涂层有利于促进钛基植入体与体内骨组织的骨结合,喷砂酸蚀处理的Ti6Al7Nb表现出良好的生物活性。
【英文摘要】
Titanium( Ti) and its alloys have been used widely as implants due to their excellent mechanical toughness,strength,corrosion resistance and biocompatibility. However,they exhibit poor osteoinductive properties because of their bioinert character. To improve their bioactivity,numerous techniques have been elaborated to enhance the surface compatibility of implants with bone. Ti and Ti6Al4 V are mostly used in the aerospace,occupied 50% of the titanium market. However,Ti has low strength and undergoes physic...