【摘要】 目的了解2型糖尿病合并肝胆疾病的危险因素。方法我院住院的2型糖尿病患者220例,其中合并肝胆疾病患者86例设为观察组,无合并肝胆疾病患者134例设为对照组。检测空腹血糖FPG、肝功能、血脂、糖化血红蛋白Hb A1C、体质量指数(BMI)等指标,行腹部B超检查,并进行多因素Logistic回归分析。结果 220例2型糖尿病患者有肝胆疾病者86例,占39.1%。糖尿病合并肝胆疾病与病程、BMI、FPG、总胆固醇TC、甘油三酯TG、低密度脂蛋白LDLC、Hb A1C呈正相关(P<0.05或0.01),而与高密度脂蛋白HDL-C呈负相关(P<0.05)。结论病程、BMI、血脂、Hb A1C等是2型糖尿合并肝胆疾病的危险因素;减重、控制血糖、降低血脂、定期腹部B超及肝功能检查可起到预防和减少2型糖尿病合并肝胆疾病的发生。更多还原

【Abstract】 Objective To investigate the risk factors of type 2 diabetes mellitus complicated with hepatobiliary disease. Methods There were 220 cases with type 2 diabetic patients hospitalized in our hospital during January 2012 and June 2014, of which 86 cases complicated with hepatobiliary disease were set as Observation Group, and 134 cases without complication with hepatobiliary disease were set as Control Group. All patients underwent detection of indicators including fasting blood glucose FPG, liver function, blood lipid, glycosylated hemoglobin Hb A1 C and body mass index(BMI), and ultrasonic-B abdominal examination. And multi-factor Logistic regression analysis was conducted. Results Of 220 cases with type 2 diabetes, 86 cases were complicated with hepatobiliary disease, accounting for 39.1%. Diabetes complicated with hepatobiliary disease was positively related to disease course, BMI, FPG, total cholesterol(TC), triglyceride(TG), low density lipoprotein(LDL-C) and Hb A1C(P<0.05 or 0.01), while negatively related to high density lipoprotein(HDL-C)(P<0.05). Conclusion Disease course, BMI, blood lipid and Hb A1 C are risk factors of diabetes complicated with hepatobiliary diseases; losing weight, controlling blood glucose, reducing blood lipid and regular ultrasonic-b abdominal examination and liver function test can prevent and reduce the incidence of diabetes complicated with hepatobiliary diseases.更多还原