Ventricular remodeling is one of pathologic mechanisms of chronic cardiac insufficiency,which is the outcome of many cardiovascular diseases such as hypertension,myocardial infarction,rheumatic heart disease and cardiomyopathy. Ventricular remodeling with high matrix metalloproteinases-9( MMP-9) is a kind of ventricular remodeling with high MMP-9 expression in myocardium,which can be found in many cardiovascular diseases. The animal models of high MMP-9 ventricular remodeling play an important role in inves...
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