【摘要】 以Brnsted酸性离子液体1-乙基-3-丁基咪唑对甲苯磺酸盐为催化剂,将芳香醛和2-甲基喹啉类化合物在无溶剂或甲苯中于120℃反应48 h,制备了一系列的1,3-二(2-喹啉基)丙烷化合物,产率56%~92%,产物结构经核磁共振波谱和高分辨质谱确证.该方法具有简便易行、产率较高等特点.更多还原

【Abstract】 An efficient synthesis of 1,3-bis( 2-quinolyl) propanes from aromatic aldehydes and 2-methyl quinolines using Brnsted acid ionic liquid 1-ethyl-3-butyl imidazol p-toluenesulfonate as catalyst was described. The reaction was heated at 120 ℃ in toluene or solvent-free for 48 h to give the desired products in yields of 56% —92%. The structures of the products were characterized by nuclear magnetic resonance spectrometry( NMR) and high-resolution mass spectrometry( HRMS). The method offers several advantages including simple work up procedure,good yields and so on.更多还原