【摘要】 目的对遗忘型轻度认知障碍的CT表现及临床演变进行了研究。方法从我院2011年12月-2014年6月收治的a MCI病例选取45人,筛选认知检查、同期记忆都无异常的54-76岁健康人群38人为健康对照组,全部自愿配合检查和量表评估。采用中国医学科学院心理研究所许淑莲主编的临床记忆量表。运用CT检测外侧裂宽度、海马回钩间距、额角指数及颞角宽度。以海马回钩间距/大脑横径的比值计算出海马指数。分析CT用于遗忘型轻度认知障碍和正常组之间的灵敏性和特异性。结果:遗忘型轻度认知障碍患者45例和健康者38人全部进入结果分析。a MCI病例组记忆等值量表评分结果及记忆商低于健康对照组(p<0.01)。脑CT的结果如下,a MCI病例组海马指数和外侧裂宽度均高于健康对照组(p<0.05)。结论遗忘型轻度认知障碍患者脑CT变化,为临床诊治提供了客观的指标,并实现对MCI老年患者的早期筛查,早期预防,为a MCI的一级预防提供有益的信息。更多还原

【Abstract】 Objective clinical development and CT manifestations of amnestic mild cognitive impairment were studied. Methods selected 45 patients from a MCI cases between December 2011 and June 2014 from the Third People’s Hospital of Foshan, then chose 38 54- 76 years old people that were healthy in cognitive check and memory as the control group to participate in the voluntary inspection and assessment. Using the clinical memory scale edited by XU Shu- lian from Psychology Institute of Chinese Academy of Medical Sciences; using CT to detect the width of lateral fissure, hippocampus hook spacing, frontal horn index and width of temporal horn.Calculated the hippocampus index at the ratio of he hippocampal hook spacing to cerebral transverse diameter.Analyzed the sensitivity and specificity of CT hetween mild cognitive impairment and normal groups. Results 45 amnestic mild cognitive impairment and 38 healthy subjects were involved in the result analysis. Both memory equivalent scale score results and memory quotient of a MCI cases were lower than control group( p <0.01).Brain CT results were as follow, both hippocampal index and lateral fissure width of a MCI cases were higher than control group( p <0.05). Conclusion brain CT changes of patients with amnestic mild cognitive impairment provide objective indicator for clinical diagnosis and treatment, make early screening and early prevention possible for aged a MCI patients, and are helpful to provide useful information for primary prevention of senile dementia.更多还原