【摘要】 目的 评价十二指肠乳头球囊扩张术及十二指肠乳头括约肌切开术治疗胆源性胰腺炎的疗效。方法 通过检索近10年PubMed、Cochrane Library、Medline、Web of Science、万方数据库、维普中文科技期刊全文数据库、中国学术期刊全文数据库,对纳入研究的方法学进行评价。研究者对纳入文献的质量进行严格评价和资料提取,使用Review manager 5.0软件对符合质量标准的RCTs行Meta分析。结果 6个RCT共546名病人纳入研究,其中治疗组(十二指肠乳头球囊扩张术)273例,对照组(十二指肠乳头括约肌切开术)273例,两组病人均行常规对症支持治疗。Meta分析结果显示:治疗组与对照组相比,病人术后1 d腹痛情况及术后1年复发胆管结石的差异具有统计学意义。结论 十二指肠乳头球囊扩张术可显著提升胆源性胰腺炎的疗效、改善预后。更多还原

【Abstract】 Objective To evaluate the effectiveness of biliary pancreatitis with endoscopic sphincterotomy and endoscopic papillary balloon dilatation.Methods We searched Pubmed,Cochrance Library,Medline,Web of Science,Wanfang Database,Weipu Database,China Science & Technology Journal Full-text Database and China Science Periodical Database over the last decade.And the methodology of literature was extracted.A manual search of those trials was simultaneously performed.Meta-analysis was conducted on the outcomes of included trials with the assistance of Review Manager5.0 software.Results Six randomized controlled trials(RCT) including 546 patients were retrieve.The treatment(endoscopic sphincterotomy,n= 273) and control(endoscopic papillary balloon dilatation) groups were assigned.Both groups received conventional supports.The differences of postoperative abdominal pain at Day 1 and postoperative recurrence of biliary calculi at Year 1 had statistical significance.Conclusions Endoscopic papillary balloon dilatation may significantly improve the curative efficacies and improve the prognosis of biliary pancreatitis.更多还原