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美多芭联合吡贝地尔治疗帕金森病的疗效观察

Evaluation on Therapeutic Effects of Combining Madopa and Piribedil in Treating Pakinson Disease

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【作者】 牟冬生张朝贵瞿昌华

【Author】 MU Dongsheng;ZHANG Chaogui;QU Changhua;Hubei Institute for Nationalites;Department of Neurology,Affiliated Hospital of Hubei Institute for Nationalites;

【机构】 湖北民族学院湖北民族学院附属民大医院神经内科

【摘要】 目的临床观察美多芭联合吡贝地尔治疗帕金森病的疗效。方法 63例帕金森病患者随机分为治疗组(33例)和对照组(32例),在常规治疗下,对照组采用美多芭,治疗组在对照组基础上加用吡贝地尔,所有患者分别在治疗前和治疗后的2个月进行改良Webester量表评定。结果 Webster评分:治疗组症状改善明显优于对照组(P<0.05),临床有效率明显高于对照组(P<0.05)。结论美多芭联合吡贝地尔治疗帕金森病有良好的临床效果,比单用美多芭治疗有效率更高。

【Abstract】 Objective To assess the therapeutic effects of Madopa( M) in combination with Piribedil( P)in Pakinson disease( PD).Methods A total of 65 patients diagnosed with PD were randomly divided into control group( n = 32) and trial group( n = 33). The patients in trial group received M +P,while M was given alone in control group.All patients were assessed with modified Webster chart before and after treatment of 2 months.Results The Wester score indicated that the syndrome of patients was improved better in the trial group than that in the control group( P<0.05). And the marked curative effect rate was significantly higher than that in the control group( P<0.05).Conclusion It was more effective to treat PD by using M+P when compared with using M alone.

【关键词】 美多芭吡贝地尔帕金森病
【Key words】 MadopapiribedilPakinson disease
  • 【文献出处】 湖北民族学院学报(医学版) ,Journal of Hubei University for Nationalities(Medical Edition) , 编辑部邮箱 ,2015年02期
  • 【分类号】R742.5
  • 【被引频次】5
  • 【下载频次】63
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