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海南省软叶针葵花粉致变应性鼻炎的临床研究

Clinic analysis of phoenix roebelenii pollen’s allergens sensitization in Hainan province

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【作者】 李春林谢伟伟刘硕孟光龙绮蔡琼香陈菊蓉

【Author】 LI Chunlin;XIE Weiwei;LIU Shuo;MENG Guang;LONG Qi;CAI Qiongxiang;CHEN Jurong;Department of Otolaryngology Head and Neck Surgery,Haikou People’s Hospital;

【机构】 海口市人民医院耳鼻咽喉头颈外科

【摘要】 目的了解海南省临床软叶针葵花粉过敏情况,为变应性鼻炎的流行病学研究及临床诊断、治疗和预防提供依据。方法对2054例变应性鼻炎患者用软叶针葵花粉过敏原进行皮肤点刺试验,然后随机选择30例软叶针葵花粉变应原点刺阳性患者进行软叶针葵花粉变应原鼻黏膜激发试验。结果 2054例皮肤点刺试验中,软叶针葵花粉变应原阳性者占67.38%(1384/2054)。30例软叶针葵花粉变应原皮肤点刺阳性患者中变应原鼻黏膜激发试验阳性者30例(100%)。20例阴性对照未见阳性反应。结论软叶针葵花粉为海南省重要变应原,皮肤点刺和变应原鼻黏膜激发试验结果相符合。这一结果可以指导本地区变应性鼻炎患者进行预防以及特异性性免疫治疗。

【Abstract】 OBJECTIVE To investigate the phoenix roebelenii pollen as the allergen of allergic rhinitis in Hainan Province and provide guidance for prevention and treatment of allergic rhinitits.METHODS A total of 2054 patients with allergic rhinitis were tested with the allergen of phoenix roebelenii pollen by skin prick test,and then choose30 positive cases to give the nasal mucosa provocation test.RESULTS The total positive rate of allergen of phoenix roebelenii pollen by skin prick test was 67.38%(1384/2054).The 30 cases with positive skin prick test were all positive in nasal mucosa provocation test and the cases in control group were all negative.CONCLUSION Phoenix roebelenii pollen is an important allergen in Hainan Province.There is a correlation between skin prick test and nasal mucosa provocation test.The allergen skin prick test can provide clue for the patients to avoid the pathogenic allergens and for the specific immunotherapy.

【基金】 国家自然科学基金(81160129);海南省自然科学基金资助项目(30871、811147);海南省国际科技合作重点计划项目(2012-GH010);海口市重点科技计划项目(海科立2007-0080号,海科工信立[2012]72号);海南省卫生厅科研项目(琼卫2007-79)联合资助
  • 【文献出处】 中国耳鼻咽喉头颈外科 ,Chinese Archives of Otolaryngology-Head and Neck Surgery , 编辑部邮箱 ,2015年10期
  • 【分类号】R765.21
  • 【被引频次】3
  • 【下载频次】48
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