【摘要】 目的研究经支气管镜行支气管肺泡灌洗术(BAL)治疗顽固发热的儿童大叶性肺炎的疗效。方法选取2012年3月至2014年2月在开封市儿童医院呼吸科住院的顽固性发热的儿童大叶性肺炎46例,随机分为两组,支气管镜治疗组25例,常规治疗组21例。常规治疗组采用阿奇霉素联合头孢曲松抗感染,氨溴索化痰,高热时行物理或药物降温;支气管镜治疗组在常规治疗的基础上采用支气管镜行支气管肺泡灌洗术进行治疗。观察两组患者住院治疗后的退热时间。结果支气管镜治疗组和常规治疗组患者经治疗后体温均降至正常。但是,支气管镜治疗组的平均退热时间为(4.6±1.2)d,常规治疗组为(6.5±2.8)d。两组患者退热时间比较差异有统计学意义(t=3.56,P<0.05)。结论经支气管镜行支气管肺泡灌洗术,治疗顽固发热的儿童大叶性肺炎,可显著地缩短患者发热时间。更多还原

【Abstract】 Objective To study the curative effect of bronchoscopic bronchial alveolar lavage( BAL) on persistent fever of lobar pneumonia in children. Methods From March 20l2 to February 20l4,46 children with persistent fever of lobar pneumonia were selected. The cases were randomly divided into two groups,with 25 cases in bronchoscopy group and 21 cases in routine treatment group. Azithromycin and ceftriaxone were used to resist infection,and ambroxol were used to dissolve phlegm,physical or drug cooling was given to reduce the fever in both groups. On the basis of conventional therapy,bronchoscopic bronchial alveolar lavage( BAL) were used in bronchoscopy group. After then,the fever reducing time of the two groups were observed.Results Patients’ body temperature decreased to normal after the treatments in both groups. However,the average defervescence time was( 4. 6 ± 1. 2) days in bronchoscopy group and( 6. 5 ± 2. 8) days in routine treatment group. There was significant difference in defervescence time between the two groups( t = 3. 56,P < 0. 05). Conclusion Bronchoscopic bronchial alveolar lavage( BAL) for persistent fever of lobar pneumonia can apparently shorten the defervescence time.更多还原