【摘要】 目的:对我院2011~2013年住院患者中分离到金黄色葡萄球菌的分布特点及其对抗菌药物的耐药性做回顾性分析,为临床预防感染和合理用药提供指导依据。方法:回顾性分析三年内住院患者细菌培养标本中金黄色葡萄球菌的分离情况及耐药性。结果:分离到的515株葡萄球菌中,以来自痰液为主(57.09%),分泌物(25.04%),血液(5.05%),科室分布为ICU(86%),骨科(68%),神经外科(55%),515株葡萄球菌中耐甲氧西林金黄色葡萄球菌(MRSA)304株。药敏结果:金黄色葡萄球菌对替考拉宁,万古霉素、利奈唑胺和喹奴普汀/达福普汀的敏感率最高,MRSA耐药性远大于MSSA。结论:金黄色葡萄球菌在医院感染逐年上升,MRSA的分离率也相应升高,临床应加强对金黄色葡萄球菌的感染预防措施,加强对MRSA的监测,并根据药敏试验结果合理使用抗菌药物。更多还原

【Abstract】 Objective: To detect the distribution, infected sites and antibiotic resistance of patients with aureus infection, providing reference for establishing the prevention and control methods of nosocomial infections from 2011~2013. Methods:The clinical data and antibiotics resistance of 515 aureus infected patients were analyzed retrospectively. Results:305 strains of Staphylococcus aureus were isolated, including 304 MRSA. The main infection site was lower respiratory tract(57.09%), secretion(25.04%), blood(5.05%); the department with Staphylococcus aureus infection were ICU(86%), Orthopaedics(68%), and neurosurgery(55%). The resistance of MRSA was higher than MSSA, MRSA were sensitive to vancomycin, linezolid and quinupristin/dalfopristin, but have higher resistant rate to other antibiotics. Conclusion:MRSA was easy distribute in the department with critically ill patients, those department should strength monitor to MRSA, The disinfection and isolation system should be strictly implemented to reduce and avoid MRSA prevalence in hospital.更多还原