节点文献

神经生长因子治疗周围神经损伤的临床研究

Clinical Research on Effects of Nerve Growth Factor on Treatment of Peripheral Nerve Injuries

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 董孟政张甲铠孟宪亮张奇

【Author】 Dong Meng-zheng;Zhang jia-kai;Meng Xian-liang;Department of Orthopaedics,Jiyang County People’s Hospital;

【机构】 山东省济阳县人民医院骨科

【摘要】 目的:观察神经生长因子(NGF)对周围神经损伤的近期治疗效果。方法:将45例周围神经损伤患者随机分为治疗组(24例)和对照组(21例),对治疗组患者进行肌肉注射NGF治疗4周。1个月后对患者疼痛、麻木症状的改善情况、患肢肌力恢复情况进行对比研究分析。结果:两组病例均获随访,两组患者的疼痛症状改善情况无明显不同;但麻木症状改善与肌力恢复情况,治疗组明显优于对照组,且差异有统计学意义(P<0.05)。结论:神经生长因子(NGF)在周围神经损伤早期对神经恢复有有效的促进作用。

【Abstract】 Objective: To observe the effects of nerve growth factor(NGF) on the early treatment of peripheral nerve injuries.Methods:45 cases with peripheral nerve injury were randomly divided into therapeutic group in which cases were treated by intramuscular injection for 4 weeks and control group.After 1 month,the changes in pain,anesthesia and myodynamia were compared between the peripheral group and the control group.Results:All of the 45 cases were followed-up.The effects of pain relief of the two groups were similar,while the therapeutic group was more outstanding in numb ease and muscle strength improve.There was statistical significance(P<0.05).Conclusion:NGF is effective for early recovery of peripheral nerve injuries.

【关键词】 神经生长因子周围神经损伤
【Key words】 Nerve growth factor(NGF)Peripheral nerveInjury
  • 【文献出处】 中国医药导刊 ,Chinese Journal of Medicinal Guide , 编辑部邮箱 ,2015年04期
  • 【分类号】R745
  • 【被引频次】5
  • 【下载频次】128
节点文献中: 

本文链接的文献网络图示:

本文的引文网络