【摘要】 目的:探讨雷贝拉唑联合莫沙必利治疗反流性食管炎(RE)的临床疗效。方法:50例RE患者,男27例,女23例,年龄20~60岁,平均40岁。随机分为治疗组和对照组,各25例。治疗组给予口服雷贝拉唑和莫沙必利治疗,对照组则给予莫沙必利治疗。治疗8周后观察两组临床症状、胃镜下分级变化、不良反应。结果:RE临床症状改善和胃镜下食管炎疗效的总有效率,治疗组均明显高于对照组(P<0.05)。两组均无严重不良反应,安全性好。结论:雷贝拉唑联合莫沙比利对RE有较好的治疗效果,不良反应较低。更多还原

【Abstract】 Objective: To explore the rabeprazole combined with mosapride in treatment of reflux esophagitis(RE) clinical curative effect. Methods: 50 cases of RE patients, male 27 cases, female 23 cases, age 20~60 years, average 40 years old. Were randomly divided into treatment group and control group, each of 25 cases. The treatment group was given oral rabeprazole met and mosapride in the treatment, the control group were given mosapride. Observed after 8 weeks of treatment, two groups of clinical symptoms, endoscopic grading changes, adverse reaction. Results: The total efficiency of RE improvement of clinical symptoms and endoscopic esophagitis curative effect of the treatment group were significantly higher than those in the control group(P<0.05). The two groups were no serious adverse reactions, good safety.Conclusion: Rabeprazole with the joint use of mosapride has a good therapeutic effect on RE, the adverse reaction is lower.更多还原