左西孟旦对急性心肌梗死并发心力衰竭患者LVEF及BNP水平的影响

【摘要】 目的探讨左西孟旦对急性心肌梗死并发心力衰竭患者左室射血分数(left ventricular ejection fraction,LVEF)及B型脑利钠肽(B type natriuretic peptide,BNP)水平的影响。方法选择急性心肌梗死并发心力衰竭患者60例,分为2组。给予对照组患者常规治疗,观察组在对照组基础上加用左西孟旦进行治疗。观察2组患者治疗前后的LVEF及BNP变化情况,并进行比较。结果治疗前,2组患者的LVEF和BNP水平比较差异无统计学意义,治疗后观察组LVEF显著高于对照组,BNP水平显著低于对照组,差异有统计学意义(均P<0.05)。结论左西孟旦治疗急性心肌梗死并发心力衰竭患者可以显著提高其LVEF水平并降低其BNP水平。更多还原

【Abstract】 Objective To explore the effects of levosimendan on LVEF and BNP levels in the patients with acute myocardial infarction complicated with heart failure. Methods 60 cases with acute myocardial infarction complicated with heart failure were randomly divided into two groups. The control group was given conventional treatment. The observation group was given Levosimendan based on the treatment of the control group. Results There were not significantly difference between the two groups of patients before treatment on LVEF and BNP levels, but after the treatment, comparedof the two groups,there were significantly difference between the two groups on LVEF and BNP level, the observed in group LVEF was significantly higher than the control group, amd the BNP was significantly lower than that of control group(all P<0.05). Conclusion The treatment of acute myocardial infarction complicated with heart failure patients can significantly improve the LVEF level and reduce the level of BNP.更多还原