Objective To study the analgesic effect and safety of fentanyl in neonates receiving mechanical ventilation. Methods Thirty neonates receiving mechanical ventilation between December 2010 and February 2011 were randomized into drug intervention group and control group(n=15 each). In addition to the conventional treatment for both groups, the drug intervention group received fentanyl as the analgesic treatment. Heart rate, respiratory rate, blood pressure changes, and premature infant pain profile(PIPP) scor...
【更新日期】
2015-10-23
【分类号】
R722.1
【正文快照】
机械通气在新生儿重症监护病房(neonatalintensive care unit,NICU)已成为一种有效治疗呼吸衰竭的手段,但气管插管是一种疼痛刺激,而新生儿对疼痛的感知比婴儿和成人更弥漫、强烈和持久,可使患儿烦躁不安,产生人机对抗[1]。疼痛对于新生儿,尤其是接受大量致痛性操作的早产儿和?