【摘要】 目的探讨冠心病患者升动脉弹性与冠状动脉狭窄程度的相关性。方法选择2013年5月-2014年5月入住我院拟诊为冠心病患者126例为研究对象,所有患者均行DSCT冠脉造影检查,根据有无冠脉狭窄分为冠脉狭窄组、无冠脉狭窄组,根据冠脉狭窄程度分为轻度狭窄组、中度狭窄组、重度狭窄组;比较不同组间主动脉弹性参数和Gensini评分。结果 1冠脉狭窄组相对直径变化率(%Ao)、膨胀性(Ao D)、顺应性(Ao C)明显低于非狭窄组,僵硬度(Ao SI)、Gensini评分明显高于非狭窄组(t=6.849-34.201,P<0.05,P<0.01);2轻度组%Ao、Ao D、Ao C明显高于中度组、重度组,Ao SI、Gensini评分明显低于中度组、重度组,中度组%Ao、Ao D、Ao C明显高于重度组,Ao SI、Gensini明显低于重度组(t=3.456-17.542,P<0.05、0.01)。3Gensini评分与Ao SI呈显著正相关(r=0.722,P<0.001),与%Ao、Ao D呈显著负相关(r=-0.432、0.261,P<0.001)。结论升主动弹性指标与冠状动脉狭窄程度有良好的相关性,定期检测升主动脉血管弹性功能有助于亚临床状态患者的早期干预与治疗更多还原

【Abstract】 Objective To study correlation of ascending aorta elastic and CT imaging features in patients with coronary heart disease. Methods 126 cases patients with CHD were selected as the research object, all patients were given DSCT coronary angiography examination, according to the presence of coronary artery stenosis were divided into coronary stenosis group and no coronary stenosis group, according to the extent of coronary stenosis were divided into mild stenosis, moderate stenosis group, severe stenosis group; ascending aorta elastic parameters and the Gensini score were compared between different groups. Results 1 Coronary stenosis group % Ao, Ao D, Ao C were was significantly than that no stenosis group, Ao SI, the Gensini score were significantly higher than no stenosis group(t=6.849-34.201, P<0.05, P<0.01); 2 Mild group % Ao, Ao D, Ao C were significantly higher than that of moderate group, severe group, Ao SI, Gensini score were significantly lower than the moderate group and severe group, moderate group % Ao, Ao D, Ao C were significantly higher than that of severe group, Ao SI, Gensini were significantly lower than the severe group(t=3.456-17.542, P<0.05,P<0.01); 3 Gensini score and Ao SI significant positive correlation(r=0.722, P<0.001), and % Ao, Ao D significant negative correlation(r=-0.432, 0.261, P<0.001). Conclusion Ascending aorta elastic and coronary artery stenosis degree have good correlation, regular detection ascending aorta elastic function help to early intervention and treatment in patients with subclinical state更多还原