【摘要】 目的:研究不同剂量丙泊酚用于门诊无痛肠镜检查对认知功能的影响。方法:90例肠镜检查患者随机均分为A、B、C三组。A组静注丙泊酚1.7mg/kg;其余两组在肠镜置入前静注芬太尼1μg/kg 2min后,B组静注丙泊酚1.7mg/kg,C组静注丙泊酚1mg/kg。全部患者于肠镜检查结束后5min行神经行为认知状态检查(NCSE),并在15min内完成。结果:90例患者均完成肠镜后NCSE测试。记忆能力测试和计算能力测试,C组的正确率均明显高于A组和B组(P<0.05)。结论:芬太尼1μg/kg加丙泊酚1mg/kg用于门诊无痛肠镜检查,不仅能提供满意的镇痛效果和检查条件,而且对认知功能无明显影响。更多还原

【Abstract】 Objective: To study the effects of propofol used in painless enteroscope examination on cognitive function. Methods: 90 patients scheduled for enteroscope examination were randomly divided into group A, B and C. The patients in group A were given propofol 1.7mg/kg. In group B and C, 2min after the patients were intravenously injected fentanyl 1μg/kg, then the patients were given propofol 1.7mg/kg and propofol 1mg/kg respectively. All the patients received neurobehavioral cognitive status examination(NCSE) test 5min after enteroscope examination and fi nished in 15 min. Results: All the 90 patients finished the NCSE test after enteroscope examination. In memory and calculation ability test, the accuracy rate of group C was obviously higher than that of group A and B(P<0.05). Conclusions: Fentanyl 1μg/kg combined propofol 1mg/kg used in painless enteroscope examination can provide satisfactory analgesic effects and check condition; Moreover, it has no obvious effects on cognitive function.更多还原