【摘要】 目的了解盐城地区献血者戊型肝炎病毒感染情况,为制定献血者戊型肝炎筛查策略提供依据。方法用ELISA法检测献血者Ig M/Ig G抗-HEV,用荧光定量PCR技术检测献血者HEV RNA。结果 631名献血者抗-HEV检测未检出Ig M+/Ig G-者;检出Ig M+/Ig G+10例,阳性率为1.58%;检出Ig M-/Ig G+阳性241例,阳性率为38.19%;未检出HEV RNA阳性。结论 HEV在盐城地区献血人群中既往感染率较高,但是否对输血安全构成威胁还需进一步研究。更多还原

【Abstract】 Objective To understand the situation on HEV infection among blood donors in Yancheng,and to provide the basis for a HEV screening strategy. Methods HEV-Ig M / Ig G antibodies were detected by ELISA in blood donors’ serum. HEV-RNA was detected by fluorescence quantitative PCR. Results After testing 631 donors’ samples,none was detected with the presence of HEV- Ig M + / Ig G-,10( 1. 58%) had Ig M + / Ig G +,241( 39. 78%) had Ig M- / Ig G +.None was positive for HEV-RNA. Conclusion HEV had a higher infection rate in earlier Yancheng blood donors,but further study is needed to investigate the potential threat of HEV to the safety of blood transfusion.更多还原