【摘要】 硬膜外脊髓电刺激(epidural spinal cord stimulation,ESCS)是一种将电极植入脊柱椎管内硬膜外腔,通过脉冲电流直接作用于脊髓神经的中枢神经功能性电刺激方法,最初应用于对慢性顽固性疼痛的抑制,之后的研究主要集中于该方法在运动功能恢复及神经系统疾病诊断等方面,现已成为神经接口与康复工程中的一个研究热点。本文通过总结ESCS在疼痛抑制、运动功能恢复中的研究进展,并结合ESCS研究背景,探讨了ESCS作用机制及刺激参数的优化。随后通过简述ESCS在运动功能恢复的应用研究,并结合ESCS刺激系统,提出了研制应用于运动功能的植入式刺激器的重要性,最后对ESCS的研究趋势进行展望。更多还原

【Abstract】 Epidural spinal cord stimulation( ESCS) uses electrodes which can be implanted in the spinal canal to stimulate central neural system directly. At first,ESCS is applied in chronic pain inhibition. Up to now,ESCS has been widely used in the recovery of motor function and diagnosis of nervous system diseases and become a research hotspot in neural interface and rehabilitation engineering. Through summarizing the research history of ESCS in pain inhibition and motor function recovery,this article discusses the mechanism of ESCS and the optimization of the stimulation parameters. Then by emphasizing the application of ESCS in motor function recovery,the attention focuses on the study of implantable stimulator applied in motor function.Finally,the article gives a brief introduction on future development of ESCS.更多还原