【摘要】 目的:探讨二次谐波联合实时超声造影定量分析对肝良恶性囊性变鉴别诊断的价值。方法:对55例肝良恶性囊性变的患者进行声学造影,分析造影强化模式,实时记录病灶区造影剂的强化过程,通过分析软件获取并分析病灶的造影定量参数。根据术后或活检病理结果分为恶性组和良性组,对比造影剂到达时间、达峰时间和造影剂峰值强度。结果:55例二次谐波均为肝囊性变,注入造影剂后,肝囊肿为薄壁无强化;肝包虫病中心见少量点状强化;肝结核球液化、肝脓肿形成期、肠癌肝转移并液化,动脉相呈厚壁"环状"强化,门静脉相及延迟相呈低强化,中心无强化。恶性组患者造影剂峰值强度和达峰时间均明显高于良性组(P<0.01)。结论:二次谐波联合实时超声造影的达峰时间和造影剂峰值强度,可以鉴别肝良恶性囊性病变的性质。更多还原

【Abstract】 Objective: To investigate the value of second harmonic combined with quantitative analysis of real-time contrast enhanced ultrasound in the differential diagnosis of liver benign and malignant cystic lesions. Methods: Fifty-five patients with liver benign and malignant cystic lesions were detected by the constrast echocardiography,the contrast enhanced mode was analyzed. The enhancement process of contrast agent in lesions was real-time recorded,the angiography quantitative parameters of the lesion was obtained and analyzed by software. The patients were divided into the benign group and malignant group,the time of contrast agent arrival and peak,and the contrast peak intensity between two groups were compared. Results: The second harmonic in 55 patients were the cystic lesions,the hepatic cyst was thin-wall without reinforcement. A few point-shaped reinforcement in the hepatic hydatid disease centre,and liquefaction of hepatic tuberculoma,liver abscess formation,liver metastases of colorectal carcinoma and liquefaction,arterial phase is thick-wall " ring " reinforcement,portal venous phase and delayed phase with low reinforcement and centre without enhancement were observed. The time of contrast agent peak and contrast peak intensity in the benign group were significantly higher than those in malignant group( P < 0. 01). Conclusions: The second harmonic combined with contrast agent peak time,and contrast peak intensity of ultrasonic contrast can distinguish the benign and malignant lesions.更多还原