目的探讨窄带成像放大内镜(magnifying endoscopy with narrow-band imaging NBI-ME)下胃黏膜肠上皮化生(intestinal metaplasia IM)的形态学特征,并结合病理学探讨NBI-ME下靶向活检诊断IM的临床运用。方法对50例患者行常规检查,窄带成像放大内镜(NBI-ME)观察胃体有无浅蓝色的嵴状结构(light blue crest LBC)、边缘透光带(marginal turbid band MTB)区域,分别在LBC、MTB区域或阴性区域活检,并对病理结果进行比较分析。结果 50例患者中,共获得112块活检组织,其中88块组织取自MTB+区域,其中病理学诊断IM:68例,灵敏度:97.1%,特异度:52.3%;24块组织取自LBC+区域,其中病理学诊断IM:22例,灵敏度:31.4%,特异度:95.2%;MTB+/LBC+区域重度IM比例最高.NBI-ME下在LBC、MTB阳性黏膜区活检可明显提高IM的检出率(P
【英文摘要】
Objective To investigate the morphologic features of gastric intestinal metaplasia(IM) using magnifying endoscopy with narrow-band imaging(ME-NBI) and its clinical use in the diagnosis of IM under ME-NBI targeted biopsy. Methods The endoscopic examination was performed on 50 patients and suspected lesions of gastric body associated with IM were further observed by ME-NBI.The biopsy specimens were obtained from regions containing light blue crest(LBC),marginal turbid band(MTB) mucosa or normal area for patho...
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