【摘要】 目的:优选腰痛颗粒剂中生物碱的最佳提取工艺。方法:采用正交试验法,以干浸膏得率、防己总碱和粉防己碱提取率为考察指标,优选总生物碱的渗漉工艺。结果:确定了最佳工艺条件为粉碎度为粗粉、乙醇浓度为60%、浸泡时间为48h,渗漉速度为2 ml·min-1·kg-1。结论:该工艺简便、快捷、稳定,可为生产提供理论依据。更多还原

【Abstract】 Objective: To study the optimum extraction conditions for Yaotong granules. Methods: An orthogonal test was adopted to optimize the percolation extraction process of total alkaloids by orthogonal experiment with the yield of dry extract and total extraction rate of tetrandrine and fangchinoline as the indices. Results: The optimal extraction conditions were as follows: the medicinal materials were soaked with crude powder in 60% ethanol for 48h,then percolated at the rate of 2 ml·min- 1·kg- 1. Conclusion: The extraction technology for Yaotong granules is simple and rapid with stable results,which can provide theoretical basis for the production of Yaotong granules.更多还原