【摘要】 近年来,由于人口老龄化、肥胖和生活方式的改变,致使糖尿病患病率增加,冠心病是糖尿病的主要并发症。研究表明,与非糖尿病相比,糖尿病冠心病患者冠状动脉病变严重,治疗矛盾多、困难大,且由于临床表现不典型,以致容易造成诊断延迟,对心肌造成不可逆的损害,至今还没有满意的防治措施。因此,科学探索糖尿病冠心病的防治策略引起广泛关注。中医理论认为糖尿病冠心病属于消渴病并心病范畴,气阴两虚兼夹燥热是其主要病机,气虚致瘀,阴虚致内热,热瘀内蕴可化毒,因此"气阴两虚、瘀毒内蕴"是糖尿病冠心病的主要病机。"滋阴益气、活血解毒"疗法是防治糖尿病冠心病的一种有效治疗策略。更多还原

【Abstract】 Currently,the prevalence of diabetes mellitus(DM) was increasing rapidly due to aging of the population,increased frequency of obesity,and the change of lifestyle. Coronary heart disease(CHD) was the major macrovascular complication of DM. It had been evident that CHD patients with DM had more serious coronary artery lesions,more conflicts and difficulties in treatments,when compared with non-diabetic counterparts. Moreover,the clinical manifestations of diabetic CHD were often untypical,and sometimes asymptomatic,diagnosis about it was often delayed in some cases,contributing to irreversible myocardial damage. At present,there was no satisfactory strategy for its prevention and treatment. Therefore,the scientific research for its prevention and treatment had caused widespread concern. According to Traditional Chinese medicine(TCM) theory,diabetic CHD was essentially belonged to the categories of Xiao Ke complicated with cardiopathy. Yin debilitation and Qi deficiency,combined with dryness-heat,were the Xiao Ke cardiopathy basic constitution. With the development of the disease,heart Qi unable to promote the blood circulation,leading to Qi stagnation and blood stasis,and the accumulation of internal heat may consume or scorch the body Yin and blood,and subsequently lead to blood stasis and change into stasis toxin.Therefore,the co-existence of deficiency of both Qi and Yin,blood stasis and toxin accumulation was the important intrinsic pathogenesis of diabetic CHO. The strategy of "Qi-supplementing and Yin-nourishing,stasis-resolving and detoxification" may served as one of the effective methods for diabetic CHD.更多还原