【摘要】 目的研究中风证候要素与大脑中动脉供血区脑梗死体积的相关性。方法纳入缺血性中风急性期患者68例,收集中医四诊信息,根据《中风病辨证诊断标准》提取证候要素并附分值,梗死灶体积采用ITKSNAP2.4.0半自动化测量,采用SPSS17.0统计软件进行数据分析。结果缺血性中风急性期证候要素出现频次最多的为风证,共计56次,占82.35%,阴虚阳亢证出现的频次最少,为15次,占22.06%,火热证、痰证、血瘀证、气虚证出现的频次依次为39次、40次、20次和25次,分别占57.35%、58.82%、29.41%和36.78%。风证,火热证及气虚证的得分与梗死灶体积呈正相关(P<0.05),其中火热证分值与梗死灶体积呈显著相关(P<0.01),痰证,血瘀证及阴虚阳亢证的得分与梗死灶体积无相关性。结论证候要素的得分与大脑中动脉供血区梗死灶体积具有一定的相关性。更多还原

【Abstract】 Objective: To identify the correlation between TCM syndromes factors of ischemic stroke and cerebral infarction volume in cerebral artery area. Methods: The patients with acute cerebral infarction were included and information of TCM four diagnostic methods were collected. The syndrome factors were extracted according to the Stroke Syndrome Diagnostic Criteria with attached scores. The cerebral infarction volume in cerebral artery area was measured by ITK-SNAP2.4.0. The data was analyzed by SPSS 17.0. Results: Wind syndrome(n=56, 82.4%) was the most frequently seen in TCM syndromes factors of ischemic stroke while yin deficiency and yang excess(n=15, 22.06%)syndrome was the least frequently seen. The frequencies of fire syndrome, phlegm syndrome, blood stasis and qi deficiency syndrome were 39(57.35%),40(58.82%),20(29.41%) and 25(36.78%) respectively. The scores of wind syndrome, fire syndrome and qi deficiency syndrome were positively correlated to the cerebral infarction volume(P < 0.05) with fire syndrome mostly significant correlated(P < 0.01). The other TCM syndromes factors had no statistical correlations. Conclusion: The scores of TCM syndromes factors are correlated to cerebral infarction volume in cerebral artery area.更多还原