【摘要】 目的:分析经皮冠状动脉介入(PCI)治疗围手术期规范应用抗生素的成效。方法:回顾性调查2011年1月-12月心血管内科择期行PCI手术患者212例作为未规范组,2012年1月-12月心血管内科对择期行PCI手术规范围手术期抗生素应用的228例作为规范组,对患者术后平均住院日、住院药物费用、抗生素使用情况、术后发热情况进行分析。结果:规范围手术期抗生素应用后,抗生素不合理使用率从97.17%下降至0%;术后住院日由5.21±2.18天下降至3.71±1.49天(P<0.05);住院药物费用从6421.1±2619.6元下降至5857.3±2493.8元(P<0.05);术后发热2组差异无统计学意义(P>0.05)。结论:依据卫生部相关规定规范PCI围术期抗生素应用,能缩短住院周期,减轻患者经济负担,不会增加术后发热发生率。更多还原

【Abstract】 [Objective]To find out and evaluate perioperative prophylactic application of antibiotics in patients undergoing coronary intervention surgery in our hospital pre and post specification.[Method]A retrospective survey was carried out.211 patients undergoing coronary intervention during Jan2011 to Dec 2011 were included in pre-specification group and228 patients undergoing coronary intervention during Jan2012 to Dec 2012 were included in post-specification group.The average length of stay,drug cost,the fever post operation and the application of antibiotics were evaluated.[Result]The perioperative prophylactic antibiotics application rate reduced from100% to 0% after specification.The average length of stay post-operation reduced to 3.71±1.49 from5.21 ±2.18 pre-specification(P=0.015)and the drug cost during hospital drop to 5857.3±2493.8 yuan from6421.1±2619.6 yuan pre-specification(P=0.032).The fever post-operation between the two groups was not statistically significant.[Conclution]It is necessary to standard the Antibiotics in Patients Undergoing Coronary Intervention according to<implement of the Guiding Principles of Clinical Use of Antibiotics> to shorten the length of stay,light the burden of the patients.Furthermore,it will not increase incidence of fever post-operation.更多还原