【摘要】 目的通过分析大连市2013年手足口病(hand-foot-mouth disease,HFMD)发病流行情况,为制定有效的预防控制策略提供依据。方法采用描述流行病学方法对2013年"中国疾病监测信息报告管理系统"报告的HFMD疫情资料和2013年大连市开展的HFMD病原学监测结果进行核实和分析。结果大连市2013年共报告HFMD 11 113例,发病率为165.33/10万,重症病例161例,死亡病例1例,发病集中在7—9月,男性多于女性,以0~6岁散居儿童为主。病原学监测结果显示,肠道病毒71型(EV71)占阳性标本的14.21%,柯萨奇病毒A组16型(Cox A16)占阳性标本的20.25%,其他肠道病毒阳性率为65.54%。抽取88份样品进行Cox A6检测,检测出39份阳性标本,阳性率44.32%。结论大连市2013年HFMD发病有明显的年龄、性别、地区和季节性差异,引起儿童HFMD的主要病原体,EV71的比例明显下降,Cox A6的比例有所上升。更多还原

【Abstract】 [Objective]To analyze the epidemiological features of hand-foot-mouth disease( HFMD) in Dalian City in 2013,provide scientific evidence for formulating effective prevention and control strategies. [Methods]By descriptive epidemiological method,the epidemic data of HFMD from the National Diseases Reporting Information System and results of HFMD pathogenic surveillance in Dalian City in 2013 were verified and analyzed. [Results]A total of 11113 HFMD cases were reported in Dalian City in 2013,with the incidence rate of 165. 33 / lakh,and there were 161 severe cases and 1death case. The peak season was July to December,male cases were more than females,and most of patients were scattered children aged 0-6 years old. The pathogenic surveillance showed that enterovirus 71( EV 71) accounted for 14. 21% of positive samples,Coxsackievirus A16( Cox A16) accounted for 20. 25%,and the positive rate of other enteroviruses was 65. 54%. 88 samples were collected to detect Cox A16,39 were positive with the positive rate of 44. 32%. [Conclusion]There are obvious age,gender,regional and seasonal features in HFMD cases in Dalian City in2013. As for the main pathogens of HFMD in children,the proportion of EV71 has decreased while that of Cox A6 has increased.更多还原