【摘要】 目的探讨婴幼儿社区获得性肺炎支原体(MP)肺炎的临床特征。方法对228例婴幼儿肺炎患儿血清采用ELISA法进行肺炎支原体抗体(MP-IgM)检测,MP-IgM阳性为MP感染组,MP-IgM阴性为对照组,并进行比较分析。结果感染组与对照组发病年龄差异有高度统计意义(P<0.01),发病季节无明显差异(P>0.05)。2组患儿均有咳嗽、喘鸣及呼吸困难,感染组高热、肺部X线片状阴影、C反应蛋白(CRP)阳性、WBC升高、肺外并发症等均高于对照组,差异均有高度统计意义(P<0.01)。结论 MP感染的婴幼儿肺炎以高热为主,且持续时间较长;WBC和CRP增高,肺部X线有肺气肿伴单侧片状阴影;肺外表现多见。对高度怀疑MP感染的患儿,应及时做MP抗体的检查以确诊。更多还原

【Abstract】 Objective To study the relation of the clinical features of community acquired pneumonia and infection of mycoplasmas pneumonia( MP) in infants. Methods The blood serum MP-IgM of 228 young children with pneumonia were detected with ELISA test,according to results of MP-IgM were divided into MP-IgM positive group and MP-IgM negative group. The clinical features in two group were contrasted. Results 48 cases of 228 patients with pneumonia were MP-IgM positive( 21. 1%). The age of under 6 months was 13 cases( 27. 1%),the range of from 6 months to 3 years was 35 cases( 72. 9%),28 cases( 58. 3%) in winter and spring and 20 cases( 41. 7%) in summer and autumn. The age of under 6 months was 133( 73. 9%) cases and from 6 months to 3 years was 47( 26. 1%) cases in MP-IgM negative group,127( 70. 6%) cases in winter and spring,53( 29. 4%) cases in summer and autumn. There was significantly difference on the age( P < 0. 01). The fever of high was 42( 87. 5%) cases,CRP positive 22( 45. 8%) cases,WBC over 10 ×109/ L 21( 43. 8%) cases and the scattered areas of consolidation the chest radiographs were found in about 24( 50%) cases in MP-IgM positive group. The rate of organ damage of extra-pulmonary organs were 20 cases( 41. 6%) and 41( 22. 5%) cases in MP-IgM positive group and in MP-IgM negative group,respectively( P < 0. 01). Conclusion It is noted that the community acquired pneumoniae caused by MP infection in young children have higher fiver with longer period and there are more other systemic manifestation and the scattered areas of consolidation on X-ray exam in chest,the C-reactive protein and the white blood cell over normal is common. The suspicious infection patients should be tested by special MP-IgM in serum in time,diagnosed and treated as early as possible.更多还原