【摘要】 目的:了解长沙地区居民酒精使用障碍与心境障碍共病的患病情况。方法:采用多阶段整群抽样方法,对15岁及以上人群进行入户调查,共抽样12 475人。以增补后的一般健康问卷12(GHQ-12)为筛选工具,将调查对象分为患精神疾病高、中、低危险组。以美国精神障碍诊断与统计手册第4版(DSM-IV)轴Ⅰ障碍定式临床检查病人版(SCID-I/P)为诊断工具。12 094人完成GHQ-12,2351人完成SCID-I/P,对这2351名居民中酒精使用障碍和心境障碍的共患情况进行分析。结果:酒精使用障碍和心境障碍的时点患病率分别为1.76%(46/2351)和6.01%(141/2351)。酒精使用障碍患者有心境障碍者占60.9%(28/46),心境障碍患者有酒精使用障碍者为19.9%(28/141)。控制年龄、性别、居住地、受教育程度、家庭年收入以后,酒精使用障碍患者发生心境障碍的风险性高于非现患酒精使用障碍者(OR=33.54,95%CI:17.52~64.20);心境障碍患者发生酒精使用障碍的风险性高于非现患心境障碍者(OR=35.11,95%CI:18.02~68.39)。结论:酒精使用障碍与心境障碍容易发生共患,应引起精神卫生工作者的重视。更多还原

【Abstract】 Objective:To investigate the comorbidity rates of alcohol use disorders and mood disorders among residents in Changsha City. Methods: In this cross-sectional household survey,12 475 residents aged 15 years or older in Changsha City w ere identified w ith multistage cluster sampling methods. A total of 12 094 residents responded and w ere screened w ith an expanded version of the General Health Questionnaire (GHQ). According to the GHQ assessment,2351 residents w ere administered a Chinese version of the Structured Clinical Interview for Diagnostic and Statistical Manual (DSM)-IV axis I disorders by psychiatrists. Then further descriptive analyses w ere conducted to investigate the comorbidity rates of alcohol use disorders and mood disorders among these 2351 individuals. Results: The time point prevalence of alcohol use disorders and mood disorders w as 1. 76% and 6. 01%, respectively. In those w ho had an alcohol use disorder,60. 9% also had a mood disorder,w hereas 19. 9% of those suffered w ith mood disorders also had an alcohol use disorder. After controlling for age,gender,regions and education levels,the higher risk of suffering mood disorders w as in persons w ith alcohol use disorders than ones w ithout alcohol use disorders (OR = 33. 54,95% CI: 17. 52 ~ 64. 20),and the higher risk of alcohol use disorders w as in persons w ith mood disorders than ones w ithout mood disorders (OR = 35. 11,95% CI: 18. 02 ~ 68. 39). Conclusion: It suggests that alcohol use disorders and mood disorders are highly comorbid,w hich should be regarded by the professionals in the field of mental health.更多还原