【摘要】 目的比较近年来慢性心房纤颤奎尼丁、乙胺碘呋酮、莫雷西嗪、索他洛尔疗效。方法在中文CNKI数据库中检索文献,纳入心房纤颤四种药物随机对照试验,采用Revman5.0软件进行Meta分析。结果以奎尼丁、乙胺碘呋酮疗效较好。有效率高于索他洛尔和莫雷西嗪,差异有统计学意义(P<0.05)。结论 Meta分析表明、在60岁之前患者,除颤成功与否与预后有密切关系,而60岁以上患者,除颤是否成功与预后关系不大,目前治疗房颤最有效、而且副作用最小的药物仍推荐乙胺碘呋酮。更多还原

【Abstract】 Objective To compare the recent years, chronic atrial fibrillation, quinidine, amiodarone, moricizine, sotalol efficacy. Methods Chinese CNKI database to retrieve documents, included four drugs atrial fi brillation randomized controlled trials, using Revman5.0 Meta-analysis software. Results quinidine, amiodarone better effi cacy. There are more effi cient than sotalol and moricizine, the difference was statistically signifi cant(P<0,05). Conclusions Meta analysis showed that 60-year-old patient before defi brillation and prognosis of the success, and people over the age of 60, whether defi brillation success and prognosis is not currently the most effective treatment of atrial fi brillation, and minimal side effects of drugs still recommend amiodarone.更多还原