【摘要】 目的探讨急性颅脑损伤患者术后颅内感染的相关危险因素,为临床预防和控制颅内感染提供依据。方法回顾性分析266例急性颅脑损伤开颅术后患者的临床资料,将导致感染的各项可能危险因素进行单因素分析,对有显著差异的结果再采用二项Logistic多元线性回归分析。结果全组病例术后发生颅内感染45例,感染率为16.9%。术前GCS评分、开放性颅脑损伤、脑室引流管放置时间、术后切口脑脊液漏以及术前合并糖尿病是急性颅脑损伤手术后颅内感染的独立危险因素。结论对具有上述危险因素的颅脑外伤的患者应采取相对应的措施加强颅内感染的防控。更多还原

【Abstract】 【Objective】 To discuss the risk factors related to intracranial infection after surgery for acute craniocerebral injury so as to put forward its prevention and treatment. 【Methods】 Clinical data of 266 cases of acute craniocerebral injury patients in our department were retrospectively analyzed. The possible risk factors related to the intracranial infection were analyzed by the single factor analysis. The significant risk factors shown by the single factor analysis were analyzed by multivariate logistic regression analysis. 【Results】 45cases of patients after craniotomy occurred intracranial infection, the infection rate was 16.9%. The multivariate logistic regression analysis showed that the independent risk factors related to the intracranial infection after the craniotomy included the GCS scores, open craniocerebral injury, ventricular drainage tube placement time, cerebrospinal fluid leakage, diabetes mellitus. 【Conclusion】 It should be pay more attention and prophylactic treatments for the acute craniocerebral injury patients with infective risk factors mentioned above.更多还原