【摘要】 目的分析许昌市流行性感冒监测结果,了解流感流行特征及毒株的型别分布,为流感防控提供科学依据。方法通过中国流感监测信息系统收集许昌市流感及流感样病例(ILI)监测资料,对其流行病学、病原学进行分析。采用狗肾传代细胞(MDCD)对流感病毒进行培养,对分离到的毒株采用血凝抑制实验进行型别和亚型鉴定。结果许昌市2011年-2013年ILI全年均有病例发生,ILI%呈上升趋势,就诊高峰出现在12月份至次年3月份;人群分布主要集中在≤15岁年龄组,占66.81%(24 915/37 291);在1 219份ILI标本中核酸阳性检出率为11.48%。77份核酸阳性标本中分离到流感病毒38株,病毒分离阳性率为49.35%。结论许昌市流感病毒活动高峰在冬季和春季,流行有明显的季节性,甲3亚型和B型病毒为主要流行株,须加强监测与防控。更多还原

【Abstract】 Objective To investigate the influenza monitoring results about influenza epidemic situation and the distribution of the virus type in Xuchang and to provide scientific basis for influenza prevention and control. Methods The monitoring data about influenza and influenza-like illness of Xuchang were collected via the China information system for influenza surveillance.The epidemiology and etiology were monitored and analyzed. The influenza virus were isolated by Madin-Darby Canine Kidney( MDCK) cell directly. The types and sub-type identification of influenza virus were confirmed by hemagglutination inhibition( HI) test. Results The influenza-like illness cases occurred all the year round in Xuchang from 2011-2013,The ILI( %) were gradually increasing,the highest levels of the ILI visits percentage were during December to March; Population distribution was mainly in the age group of under 15 years old,accounting for 66. 81%( 24 915 /37 291); The positive rate of nucleic was 11. 48% in 1 219 ILI specimens. 38 influenza viruses were isolated in 77 positive of nucleic,virus isolation positive rate was 49. 35%. Conclusion The peak of influenza virus activities in Xuchang area was in winter and spring. There were significant seasonal epidemic,and A 3 sub-types and type B were major epidemic strain. It is necessary to strengthen viral surveillance and prevention.更多还原