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临床肺癌诊断中肿瘤标志物CA153、CA125检验应用的价值分析

Clinical application value analysis of tumor markers CA153,CA125 test in the diagnosis of lung cancer

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【作者】 张宝凯张静马希祥

【Author】 ZHANG Bao-kai;ZHANG Jing;MA Xi-xiang;Clinical Laboratory,Binzhou People’s Hospital;

【机构】 滨州市人民医院检验科

【摘要】 目的探讨肺癌临床诊断中肿瘤标志物CA153、CA125检验应用的价值。方法统计分析2012年1月-2014年1月本院收治的100例肺癌患者的临床资料。结果观察组患者肿瘤标志物CA153、CA125检测水平异常率分别为54%(54/100)、83%(83/100)均明显比对照组12%(12/100)、17%(17/100)高(P<0.05);CA153+CA125的灵敏度和正确诊断指数均明显比CA153、CA125高(P<0.05);鳞癌患者的血清CA125水平明显比腺癌、小细胞癌患者高(P<0.05),且腺癌患者的血清CA125水平明显比小细胞癌高(P<0.05)。结论肺癌临床诊断中肿瘤标志物CA153、CA125联合检验具有较高的应用价值。

【Abstract】 Objective To study the clinical application value of tumor markers CA153,CA125 test in diagnosis of lung cancer.Methods The clinical data of 100 cases of lung cancer patients in our hospital from January 2012 to January 2014 were statistically analyzed.Results The abnormal rates of tumor marker CA153,CA125 test levels in the observation group(54%(54/100),83%(83/100)) were significantly higher than in the control group(12%(12/100),17%(17/100))(P < 0.05);the sensitivity and correct diagnosis index of CA153 + CA125 were significantly higher than CA153,CA125(P < 0.05);the serum CA125 level of squamous cell carcinoma was significantly higher than squamous cell carcinoma and small cell carcinoma(P <0.05),and the serum CA125 levels of adenocarcinoma was significantly higher than small cell carcinoma(P < 0.05).Conclusion The joint test of tumor markers CA153,CA125 has higher clinical application value in the diagnosis of lung cancer.

  • 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2014年22期
  • 【分类号】R734.2
  • 【被引频次】14
  • 【下载频次】128
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