【摘要】 目的探究婴幼儿支气管哮喘患儿的尿白三烯E4(LTE4)水平,探讨其在婴幼儿哮喘发病及治疗中的意义。方法收集30例支气管哮喘婴幼儿的尿液,30例健康婴幼儿的尿液用做对照,采用ELISA方法检测尿中白三烯E4的水平。结果婴幼儿支气管哮喘患儿尿LTE4水平(380.66±115.76)ng/ml,对照儿童尿LTE4水平(263.52±46.21)ng/ml。支气管哮喘患儿LTE4水平明显高于对照组,P<0.01。结论婴幼儿患支气管哮喘时尿白三烯E4水平显著升高,提示白三烯水平与支气管哮喘发生有关,可以作为诊断婴幼儿支气管哮喘的辅助诊断性指标。更多还原

【Abstract】 Objective To explore the infant asthma in children with urinary leukotriene E4(LTE4) level,explore the pathogenesis and treatment of infants with asthma significance.Methods 30 urine samples were collected from infants with asthma,30 healthy infant urine used as control,using the ELISA method for detection of urinary leukotriene E4 level.Results the infant asthma in children with urinary LTE4 levels(380.66±115.76)ng/ml,the control children urinary LTE4 levels(263.52±46.21)ng/ml.The level of LTE4 in children with bronchial asthma was significantly higher than the control group,P<0.01.Conclusion urinary leukotriene E4level increased significantly in infants suffering from bronchial asthma,leukotriene levels and prompted bronchial asthma,can be used as auxiliary diagnostic index for the diagnosis of infantile bronchial asthma.更多还原