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全身炎症反应综合征修正评分及白细胞监测鉴别脑外伤患者应激反应与早期感染的价值

Value of systemic inflammatory response syndrome corrected score and differential leukocyte monitoring in the diagnosis of stress response and early infection in patients with brain trauma

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【作者】 肖志强司金春许志杰申明峰

【Author】 XIAO Zhiqiang;SI Jinchun;XU Zhijie;SHEN Mingfeng;The NO.1 Neurosurgery of the First People’s Hospital of Shangqiu;

【机构】 商丘市第一人民医院神经外一科商丘医学高等专科学校商丘市第四人民医院神经外科

【摘要】 目的探讨全身炎症反应综合征修正(ASS)评分及白细胞监测鉴别应激反应和感染的应用价值。方法选择性分析2009年6月至2012年6月于本院接受治疗的脑外伤患者80例,根据是否发生早期感染分为感染组和非感染组,每组各40例。在入院7 d内对患者进行ASS评分,并于入院后前7 d以及第10、14、21 d对患者进行外周WBC监测并记录最高体温。结果感染组患者ASS平均得分(8.873±2.366)分;非感染组平均得分为(3.896±1.350)分,感染组ASS评分显著高于未感染组(t=12.347,P<0.05);应激反应所致体温及外周白细胞水平异常在伤后第1天最为明显,以后呈下降趋势,感染组患者下降后再次上升。结论患者伤后14~21 d的体温及白细胞走势对早期感染的诊断具有指示意义,ASS评分对早期感染有预测价值,可有助于鉴别应激反应与早期感染。

【Abstract】 Objective To investigate the application value of systemic inflammatory response syndrome corrected score(ASS) and leukocyte differential stress response and infection monitoring in patients with brain trauma. Methods Total of 80 patients with brain trauma from June 2009 to June 2012 in our hospital were divided into early infection group and non-infection group according to whether had infection(40 cases in each group). After admission, the WBC and the highest temperature of the patients were monitored at the first 7 days and the at the 10th, 14th and 21st days, respectively. Results The average ASS score of the infected patients was(8.873 ± 2.366) points; in non-infected group, the average score was(3.896 ± 1.350) points, with significant difference(t = 12.347, P < 0.05). First day after injury, the anormal of body temperature and peripheral leukocytes which caused by stress response was most obvious, then they had a downward trend. In infection group, they will rised again after a fall. Conclusions Among 14-21 d after injury, body temperature and white blood cell movements in the early diagnosis of infection with a direction sense, ASS score predictive value of early infection, could help identify stress response and early infection.

  • 【文献出处】 中华实验和临床感染病杂志(电子版) ,Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) , 编辑部邮箱 ,2014年02期
  • 【分类号】R651.15
  • 【被引频次】14
  • 【下载频次】90
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