【摘要】 对近几年抗甲流天然药物有效成分(挥发油类、黄酮类、多糖类、生物碱类、萜类、酚类、芪类)的研究发展进行概述,为甲型流感的防治提供参考。天然药物的有效成分不仅可以通过作用于甲型流感病毒生命周期的各阶段来直接抑制病毒,还可通过多种途径提高机体免疫机能从而防治甲流及其引起的并发症。抗流感病毒的西药作用靶点较单一,具有不同程度的毒副作用,且长期使用易产生耐药性。我国在运用天然药物防治病毒性疾病的领域拥有几千年的历史和经验,与西药相比,抗甲流天然药物具有多靶点,低毒副作用的优势,近年来越来越多的科研工作者运用实验药理学方法来研究天然药物及其化学成分的抗甲流作用,并取得了可喜的成果。更多还原

【Abstract】 Influenza A virus has a wide range of host animals and mutates easily. Nowadays anti-influenza A drugs used in clinic limit to two main classes which are the M2 ion channel blocker and the viral neuraminidase inhibitors. So some virus strains have shown drug resistance in some areas. Natural medicine or traditional Chinese medicine has a long history in China. With the development of science and technology,more and more scientific researchers use experimental pharmacology methods to study natural medicines for preventing and treating influenza A. Natual medicine has shown great potential and advantages in clinical and scientific research because of its wide biological activity and low toxicity. This paper introduces some active ingredients of anti-influenza A virus in natural medicines discovered in recent years.更多还原